Bendamustine Hydrochloride

Alternative_name

5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride
Description

Bendamustine is a novel alkylating agent with a benzimidazole ring giving it purine analogue-like properties. Like other alkylating agents, bendamustine is thought to act by modifying and cross linking purine bases in DNA, thus inhibiting DNA, RNA and protein synthesis and leading to cell death in rapidly dividing cells. Bendamustine appears to have a special activity against B cell leukemias and lymphomas.
CAS Number

3543-75-7
Structure Available

Yes
Molecular Formula

C₁₆H₂₁Cl₂N₃O₂.HCl
Molecular Weight

394.71
Cell Permeable

Yes
Purity

≥98%
Solubilities

DMSO (>30 mg/ml) or EtOH (>20 mg/ml)
Handling

Protect from air and moisture
Tag Line

An anticancer agent
Storage Condition

-20°C
Shipping Condition

Gel Pack
Shelf Life

36 months
MDL Number

MFCD16879055
PubChem CID

77082
PubChem CID Link
SMILES

CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl
InChi

InChI=1S/C16H21Cl2N3O2.ClH/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H
InChi Key

ZHSKUOZOLHMKEA-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes