BBT-594

• Catalog number
  B2114-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  5-((6-acetamidopyrimidin-4-yl)oxy)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)indoline-1-carboxamide; NVP-BBT594
• Description
  BBT-594 is a potent and selective RET and JAK2 inhibitor. It impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells. Displays potent anticancer activity.
• CAS Number
  882405-89-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₈H₃₀F₃N₇O₃
• Molecular Weight
  569.59
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent and selective RET and JAK2 inhibitor.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  59596344
• PubChem CID Link
• SMILES
  CC(=O)NC1=CC(=NC=N1)OC2=CC3=C(C=C2)N(CC3)C(=O)NC4=CC(=C(C=C4)CN5CCN(CC5)C)C(F)(F)F
• InChi
  InChI=1S/C28H30F3N7O3/c1-18(39)34-25-15-26(33-17-32-25)41-22-5-6-24-19(13-22)7-8-38(24)27(40)35-21-4-3-20(23(14-21)28(29,30)31)16-37-11-9-36(2)10-12-37/h3-6,13-15,17H,7-12,16H2,1-2H3,(H,35,40)(H,32,33,34,39)
• InChi Key
  VQLNKQZLPGLOSI-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BBT-594  
• Short name
  BBT-594
• Alternative name
  BBT-594

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