Balicatib
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Catalog number2596-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(4-propylpiperazin-1-yl)benzamide; AAE581
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DescriptionCell-permeable. Balicatib is a potent human cathepsin K inhibitor in vitro (IC₅₀ = 1.4 nM) with a high selectivity against human cathepsins B, L, and S (> 4,800-fold, > 500-fold and > 65,000-fold, respectively).
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CAS Number354813-19-7
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Structure AvailableY
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Salt FormNo
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Molecular FormulaC₂₃H₃₃N₅O₂
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Molecular Weight411.54
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Cell PermeableYes
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Purity>98% by HPLC
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SolubilitiesDMSO (~ 4 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent cathepsin K inhibitor
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Storage Condition-20 ̊C
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Shipping ConditionGel pack
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Shelf Life36 months
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PubChem CID10201696
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SMILESCCCN1CCN(C2=CC=C(C(NC3(C(NCC#N)=O)CCCCC3)=O)C=C2)CC1
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InChiInChI=1S/C23H33N5O2/c1-2-14-27-15-17-28(18-16-27)20-8-6-19(7-9-20)21(29)26-23(10-4-3-5-11-23)22(30)25-13-12-24/h6-9H,2-5,10-11,13-18H2,1H3,(H,25,30)(H,26,29)
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InChi KeyLLCRBOWRJOUJAE-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameBalicatib
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Alternative nameBalicatib
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