Atractyloside Potassium salt

Alternative_name

(2β)-15α-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic acid, dipotassium salt
Description

Atractyloside is an extremely toxic glycoside isolated from thistles. It blocks mitochondrial ATP synthesis by inhibiting ADP/ATP translocases, which are responsible for the exchange of adenine di- and triphosphates across the inner mitochondrial membrane.
CAS Number

102130-43-8
Structure Available

Yes
Salt Form

No
Molecular Formula

C₃₀H₄₄K₂O₁₆S₂
Molecular Weight

802.99
Cell Permeable

True
Purity

≥95%
Solubilities

~10 mg/ml Water
Handling

Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Tag Line

Inhibitor of ADP/ATP translocases
Storage Condition

-20ºC
Shipping Condition

Gel Pack
Shelf Life

36 months
PubChem CID

12299879
PubChem CID Link
SMILES

CC(C)CC(=O)OC1C(C(C(OC1OC2CC(C3CCC45CC(CCC4C3(C2)C)C(=C)C5O)C(=O)O)CO)OS(=O)(=O)[O-])OS(=O)(=O)[O-].[K+].[K+]
InChi

InChI=1S/C30H46O16S2.2K/c1-14(2)9-22(32)44-25-24(46-48(39,40)41)23(45-47(36,37)38)20(13-31)43-28(25)42-17-10-18(27(34)35)19-7-8-30-11-16(15(3)26(30)33)5-6-21(30)29(19,4)12-17;;/h14,16-21,23-26,28,31,33H,3,5-13H2,1-2,4H3,(H,34,35)(H,36,37,38)(H,39,40,41);;/q;2*+1/p-2/t16-,17-,18-,19-,20-,21+,23-,24+,25-,26+,28+,29-,30-;;/m1../s1
InChi Key

IUCNQFHEWLYECJ-VCQILIGCSA-L
Data Sheet Link
MSDS Available

True