Artesunate

• Catalog number
  B2332-250
• Price
  Please ask
• Size
  250 mg

• Alternative_name
  WR-256283,NSC-712571,Artesunic acid,butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester
• Description
  Artesunate is a semisynthetic derivative of artemisinin. It acts on the electron transport chain, generates local reactive oxygen species, and causes the depolarization of the mitochondrial membrane. It inhibits TNFα-induced production of proinflammatory cytokines via inhibition of NF-κB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes. Displays cytotoxic action against cancer cell lines of different tumor types. Also induces ferroptosis.
• CAS Number
  88495-63-0
• Structure Available
  Yes
• Molecular Formula
  C₁₉H₂₈O₈
• Molecular Weight
  384.42
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  >10 mg/ml (DMSO) in 0
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  Artesunate is a semisynthetic derivative of artemisinin
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00866204
• PubChem CID
  65664
• PubChem CID Link
• SMILES
  CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C
• InChi
  InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18-,19-/m1/s1
• InChi Key
  FIHJKUPKCHIPAT-NKHDUEHSSA-N
• Data Sheet Link

• Gene target
  Artesunate  
• Short name
  Artesunate
• Alternative name
  Artesunate

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