(-)-Arctigenin

• Catalog number
  B2786-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one,Arctigenin
• Description
  Arctigenin is a lignan found in the root of A. lappa. It displays antioxidant, anti-inflammatory, antiproliferative, and antiviral activity. At 0.1 μM, arctigenin can block the activation of Akt induced by glucose starvation in pancreatic cancer PANC-1 cells, which is a key process in the tolerance exhibited by cancer cells to glucose starvation. Arctigenin also demonstrates a therapeutic effect in ischemic stroke treatment of middle cerebral artery occluded rats by suppressing microglia activation and decreasing IL-1β and TNF-α expression.
• CAS Number
  7770-78-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₂₄O₆
• Molecular Weight
  372.41
• Cell Permeable
  1
• Purity
  ≥98%
• Solubilities
  >5 mg/ml Ethanol, >30 mg/ml DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A biologically active lignan
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00870597
• PubChem CID
  64981
• PubChem CID Link
• SMILES
  COC1=C(C=C(C=C1)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC)OC
• InChi
  InChI=1S/C21H24O6/c1-24-18-7-5-13(11-20(18)26-3)8-15-12-27-21(23)16(15)9-14-4-6-17(22)19(10-14)25-2/h4-7,10-11,15-16,22H,8-9,12H2,1-3H3/t15-,16+/m0/s1
• InChi Key
  NQWVSMVXKMHKTF-JKSUJKDBSA-N
• Data Sheet Link
• MSDS Available
  1

• Gene target
  Arctigenin  
• Short name
  (-)-Arctigenin
• Alternative name
  (-)-Arctigenin

Product images

Similar products