Apremilast

• Catalog number
  2352-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
• Description
  Apremilast is a potent PDE4 (phosphodiesterase 4) inhibitor (IC₅₀ = 74 nM). It reduces TNF-α production in human synovial cells and significantly suppresses experimental arthritis.
• CAS Number
  608141-41-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₂₄N₂O₇S
• Molecular Weight
  460.5
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (80 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A potent PDE4 (phosphodiesterase 4) inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11561674
• PubChem CID Link
• SMILES
  CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
• InChi
  InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
• InChi Key
  IMOZEMNVLZVGJZ-QGZVFWFLSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Apremilast  
• Short name
  Apremilast
• Alternative name
  Apremilast

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