APD-597
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Catalog number9637-50
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PricePlease ask
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Size50 mg
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Alternative_namePropan-2-yl 4-[5-methoxy-6-[(2-methyl-6-methylsulfonylpyridin-3-yl)amino]pyrimidin-4-yl]oxypiperidine-1-carboxylate; JNJ-38431055
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DescriptionAPD-597 is a GPR119 agonist with EC₅₀ of 46 nM for hGPR119. Could be a potential anti-diabetic agent for treatment of type 2 diabetes.
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CAS Number897732-93-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₁H₂₉N₅O₆S
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Molecular Weight479.55
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA second generation agonist of the orphan G-protein coupled receptor GPR119
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID11691484
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SMILESCC1=C(C=CC(=N1)S(=O)(=O)C)NC2=C(C(=NC=N2)OC3CCN(CC3)C(=O)OC(C)C)OC
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InChiInChI=1S/C21H29N5O6S/c1-13(2)31-21(27)26-10-8-15(9-11-26)32-20-18(30-4)19(22-12-23-20)25-16-6-7-17(24-14(16)3)33(5,28)29/h6-7,12-13,15H,8-11H2,1-5H3,(H,22,23,25)
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InChi KeyWPDCHTSXOPUOII-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolMIR597
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Short nameAPD-597
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Alternative nameAPD-597
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Gene info
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Identity
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Gene
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Long gene namemicroRNA 597
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Synonyms gene
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Synonyms
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Locus
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Discovery year2006-05-16
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNAs