APD-597

• Catalog number
  9637-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  Propan-2-yl 4-[5-methoxy-6-[(2-methyl-6-methylsulfonylpyridin-3-yl)amino]pyrimidin-4-yl]oxypiperidine-1-carboxylate; JNJ-38431055
• Description
  APD-597 is a GPR119 agonist with EC₅₀ of 46 nM for hGPR119. Could be a potential anti-diabetic agent for treatment of type 2 diabetes.
• CAS Number
  897732-93-3
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₂₉N₅O₆S
• Molecular Weight
  479.55
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A second generation agonist of the orphan G-protein coupled receptor GPR119
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11691484
• PubChem CID Link
• SMILES
  CC1=C(C=CC(=N1)S(=O)(=O)C)NC2=C(C(=NC=N2)OC3CCN(CC3)C(=O)OC(C)C)OC
• InChi
  InChI=1S/C21H29N5O6S/c1-13(2)31-21(27)26-10-8-15(9-11-26)32-20-18(30-4)19(22-12-23-20)25-16-6-7-17(24-14(16)3)33(5,28)29/h6-7,12-13,15H,8-11H2,1-5H3,(H,22,23,25)
• InChi Key
  WPDCHTSXOPUOII-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  APD-597  
• Gene symbol
  MIR597
• Short name
  APD-597
• Alternative name
  APD-597

Gene info

• Identity
  HGNC:32853
• Gene
  MIR597
• Long gene name
  microRNA 597
• Synonyms gene
  • MIRN597
• Synonyms
  • hsa-mir-597
• Locus
  8p23.1
• Discovery year
  2006-05-16
• Entrez gene record
  693182
• RefSeq identity
  • NR_030327
• Classification
  • MicroRNAs

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