Anti-PPP4C Antibody (2F11-D10-G4)

• Catalog number
  A1343-100
• Price
  334.8 USD
• Size
  100 µg

• Antibody Target
  Serine/threonine-protein phosphatase 4 catalytic subunit
• Target Alternative Name
  Pp4, Protein phosphatase X, PP-X, PPP4C, PPP4, PPX
• Antibody Type
  Monoclonal
• Clone
  2F11-D10-G4
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human Protein Phosphatase 4C protein fragments expressed in E.coli
• Accession
  P60510
• Gene Id
  5531
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol
• Purification
  Affinity purified
• Application
  WB, IF
• Positive Control
  WB: Hela and Jurkat cell lysates; IF: HeLa cells; IHC: human breast cancer tissue
• Application And Usages
  WB; 1:200, IF; 1:200
• Description
  Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PPP4C   2F11-D10-G4  
• Gene symbol
  PPP4C, C6orf47, PPP2R3C
• Short name
  Anti-PPP4C Antibody (2F11-D10-G4)
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG2a
• Alternative name
  Antibody toPPP4C (antibody to-) (2F11-D10-G4)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9319
• Gene
  PPP4C
• Long gene name
  protein phosphatase 4 catalytic subunit
• Synonyms gene name
  • protein phosphatase 4 (formerly X), catalytic subunit
  • protein phosphatase 4, catalytic subunit
• Synonyms
  • PP4
  • PPX
• Synonyms name
  • protein phosphatase X, catalytic subunit
• Locus
  16p11.2
• Discovery year
  1993-01-22
• Entrez gene record
  5531
• Pubmed identfication
  • 9177794
• RefSeq identity
  • NM_002720
• Classification
  • Protein phosphatase catalytic subunits
• VEGA ID
  OTTHUMG00000132113

Gene info

• Identity
  HGNC:19076
• Gene
  C6orf47
• Long gene name
  chromosome 6 open reading frame 47
• Synonyms
  • D6S53E
  • G4
• GenBank acession
  • AF129756
• Locus
  6p21.33
• Discovery year
  2002-08-13
• Entrez gene record
  57827
• Pubmed identfication
  • 2477242
• RefSeq identity
  • NM_021184
• VEGA ID
  OTTHUMG00000031172

Gene info

• Identity
  HGNC:17485
• Gene
  PPP2R3C
• Long gene name
  protein phosphatase 2 regulatory subunit B''gamma
• Synonyms gene
  • C14orf10
• Synonyms gene name
  • chromosome 14 open reading frame 10
  • protein phosphatase 2 (formerly 2A), regulatory subunit B''
• Synonyms
  • FLJ20644
  • G4-1
  • G5PR
• GenBank acession
  • AK000651
• Locus
  14q13.2
• Discovery year
  2002-11-18
• Entrez gene record
  55012
• Pubmed identfication
  • 12167160
  • 16129705
• RefSeq identity
  • NM_017917
• Classification
  • Protein phosphatase 2 regulatory subunits
• VEGA ID
  OTTHUMG00000140224

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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