Anti-PD-1 (Nivolumab), Humanized Antibody
#
-
Catalog numberA1307-100
-
Price:
-
Size100 µg
-
-
Antibody TargetPD-1
-
Target Alternative NameOpdivo, PD-1
-
Antibody TypeMonoclonal
-
Species ReactivitiesHuman
-
Immunogen SequenceHuman programmed cell death 1 receptor (PD1)
-
AccessionQ02242
-
Gene Id18566
-
AppearanceColorless liquid
-
FormLiquid
-
FormulationIn phosphate buffered saline, pH 7.6
-
PurificationAffinity purified
-
ApplicationNeutralization, ELISA
-
Application And UsagesNeutralization: 0.1-1 μg/ml, ELISA: 1 μg/ml
-
DescriptionNivolumab, trade name Opdivo, is a medication used to treat cancer. It is used as a first line treatment for inoperable or metastatic melanoma in combination with ipilimumab if the cancer does not have a mutation in BRAF, as a second-line treatment following treatment with ipilimumab and if the cancer has a mutation in BRAF, with a BRAF inhibitor, as a second-line treatment for squamous non-small cell lung cancer, and as a second-line treatment for renal cell carcinoma.
-
Storage Condition-20 °C
-
Shipping Conditiongel pack
-
Shelf Life12 months
-
UsageFor Research Use Only! Not to be used in humans
-
HandlingThe antibody solution should be gently mixed before use
-
Western Blot VerifiedNot Verified
-
Immunocytochemistry VerifiedNot Verified
-
Immunofluorescence VerifiedNot Verified
-
Immunoprecipitation VerifiedNot Verified
-
FACS VerifiedNot Verified
-
ELISA VerifiedNot Verified
-
ChIP VerifiedNot Verified
-
Dot Blot VerifiedNot Verified
-
Flow Cytometry VerifiedNot Verified
-
Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolPDCD1, ENPP2, SPATA2, SNCA, ENPP3, PDCD1LG2, CD274, IGHVII-1-1, MIR1-1, TRUND-NNN8-1
-
Short nameAnti-PD-1 (Nivolumab), Humanized Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
IsotypeHuman IgG4
-
Alternative nameAntibody toPD-1 (Nivolumab), Humanized (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameprogrammed cell death 1
-
Synonyms gene
-
Synonyms gene name
- systemic lupus erythematosus susceptibility 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1994-05-24
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- V-set domain containing
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameectonucleotide pyrophosphatase/phosphodiesterase 2
-
Synonyms gene
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1995-08-10
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namespermatogenesis associated 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-03-15
-
Entrez gene record
-
RefSeq identity
-
Classification
- Protein phosphatase 1 regulatory subunits
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesynuclein alpha
-
Synonyms gene
-
Synonyms gene name
- Parkinson disease (autosomal dominant, Lewy body) 4
- synuclein, alpha (non A4 component of amyloid precursor)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1995-01-24
-
Entrez gene record
-
Pubmed identfication
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameectonucleotide pyrophosphatase/phosphodiesterase 3
-
Synonyms gene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1995-08-10
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameprogrammed cell death 1 ligand 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2003-11-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- B7 family
- CD molecules
- Immunoglobulin like domain containing
- Receptor ligands
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameCD274 molecule
-
Synonyms gene
-
Synonyms gene name
- programmed cell death 1 ligand 1
- CD274 antigen
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2003-11-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Receptor ligands
- C2-set domain containing
- V-set domain containing
- B7 family
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
-
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-04-17
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin heavy locus at 14q32.33
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1-1
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1/206 family
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-undetermined (NNN) 8-1
-
Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
-
GenBank acession
-
Locus
-
Discovery year2014-06-20
-
Entrez gene record
-
Pubmed identfication
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data