Anti-MEK2 (KO Validated) Antibody

• Catalog number
  A2124-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  MEK2
• Target Alternative Name
  CFC4; MAPKK2; MEK2; MKK2; PRKMK2; MAP2K2
• Antibody Type
  Monoclonal
• Species Reactivities
  Mouse,Human
• Immunogen Sequence
  Synthetic peptide derived from human MEK2
• Accession
  P36507
• Gene Id
  5605
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
• Purification
  Affinity purified
• Application
  Western Blotting
• Application And Usages
  WB 1:500 - 1:2000
• Description
  The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  1
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MEK2   Validated  
• Gene symbol
  MAP2K2
• Short name
  Anti-MEK2 (KO Validated) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  IgG
• Alternative name
  Antibody toMEK2 (KO Validated) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6842
• Gene
  MAP2K2
• Long gene name
  mitogen-activated protein kinase kinase 2
• Synonyms gene
  • PRKMK2
• Synonyms
  • MEK2
• GenBank acession
  • L11285
• Locus
  19p13.3
• Discovery year
  1993-11-05
• Entrez gene record
  5605
• Pubmed identfication
  • 8388392
• Classification
  • Mitogen-activated protein kinase kinases
• VEGA ID
  OTTHUMG00000134286
• Locus Specific Databases
  • LRG_750

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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