Anti-GOT1 Antibody

• Catalog number
  A1272-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  GOT1
• Target Alternative Name
  Aspartate aminotransferase cytoplasmic; cAspAT; Cysteine aminotransferase cytoplasmic; Cysteine transaminase cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Rat
• Immunogen Sequence
  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GOT1
• Accession
  P17174
• Gene Id
  2805
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  WB
• Positive Control
  WB: Jurkat, A549, PC12, H9C2 whole cell lysates.
• Application And Usages
  WB; 1:500 – 1:1000
• Description
  Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GOT1  
• Gene symbol
  GOT1-DT, GOT1, GOLT1B, GOLT1A
• Short name
  Anti-GOT1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toGOT1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:55848
• Gene
  GOT1-DT
• Long gene name
  GOT1 divergent transcript
• Locus
  10q24.2
• Discovery year
  2021-09-01
• Entrez gene record
  101927300
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:4432
• Gene
  GOT1
• Long gene name
  glutamic-oxaloacetic transaminase 1
• Synonyms gene name
  • glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
  • glutamic-oxaloacetic transaminase 1, soluble
• Synonyms
  • AST1
• Synonyms name
  • aspartate aminotransferase 1
  • aspartate transaminase 1
  • glutamate oxaloacetate transaminase 1
• GenBank acession
  • M37400
• Locus
  10q24.2
• Discovery year
  2001-06-22
• Entrez gene record
  2805
• Pubmed identfication
  • 1974457
• RefSeq identity
  • NM_002079
• VEGA ID
  OTTHUMG00000018882

Gene info

• Identity
  HGNC:20175
• Gene
  GOLT1B
• Long gene name
  golgi transport 1B
• Synonyms gene name
  • golgi transport 1 homolog B (S. cerevisiae)
• Synonyms
  • CGI-141
  • YMR292W
  • GOT1
• GenBank acession
  • AB097020
• Locus
  12p12.1
• Discovery year
  2005-02-07
• Entrez gene record
  51026
• Pubmed identfication
  • 12414650
  • 10810093
• RefSeq identity
  • NM_016072
• VEGA ID
  OTTHUMG00000169133

Gene info

• Identity
  HGNC:24766
• Gene
  GOLT1A
• Long gene name
  golgi transport 1A
• Synonyms gene name
  • golgi transport 1 homolog A (S. cerevisiae)
• Synonyms
  • FLJ42654
  • CGI-141
  • YMR292W
  • GOT1
  • MGC62027
• GenBank acession
  • BC058832
• Locus
  1q32.1
• Discovery year
  2005-02-07
• Entrez gene record
  127845
• Pubmed identfication
  • 26255816
• RefSeq identity
  • NM_198447
• VEGA ID
  OTTHUMG00000036056

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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