Anti-Dectin-2 Monoclonal Antibody (Clone: ABM2H28)

• Catalog number
  A1533-50
• Price
  Please ask
• Size
  50 µg

• Antibody Target
  Dectin-2
• Target Alternative Name
  CLEC6A, CLECSF10, DECTIN2
• Antibody Type
  Monoclonal
• Clone
  ABM2H28
• Species Reactivities
  Human, mouse
• Immunogen Sequence
  A partial length recombinant Dectin-2 protein (amino acids 70-230) was used as the immunogen
• Accession
  Q6EIG7
• Gene Id
  93978
• Appearance
  Colorless Liquid
• Form
  Liquid
• Formulation
  0.5 mg/ml in Supplied in PBS containing 0.05% BSA and 0.05% Sodium azide.
• Purification
  Protein G Chromatography
• Application
  WB, FACS, IHC
• Application And Usages
  WB: 2-4 mg/ml; FACS: 0.5 mg/106 cells; IHC: 5 mg/ml
• Description
  Dectin-2 (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. Dectin-2 plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. It binds high-mannose carbohydrates in a Ca(2+)-dependent manner. In Dectin-2 glycosylation occurs at Asn131, Asn170. Dectin-2 has 2 isoforms produced by alternative splicing. Dectin-2 is strongly expressed in monocytes and weakly in B-cells and also expressed in spleen, tonsils, lymph node, lungs, leukocytes, dendritic cells and bone marrow.
• Storage Condition
  4°C
• Shipping Condition
  gel pack
• Shelf Life
  6 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  2-4 mg/ml
• Immunocytochemistry Verified
  5 mg/ml
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  False.5 mg/1False6 cells
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  0.5 mg/106 cells
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  Dectin-2   Monoclonal   ABM2H28  
• Short name
  Anti-Dectin-2 Monoclonal Antibody (Clone: ABM2H28)
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Isotype
  IgG2 Kappa
• Alternative name
  Antibody toDectin-2 monoclonal (antibody to-) (clonality: ABM2H28)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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