Anti-Cyclin H Antibody (1H9-D3-E11)
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Catalog number
A1320-100
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Price
Please ask
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Size
100 µg
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Antibody Target
Cyclin-H
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Target Alternative Name
Cyclin-H, MO15-associated protein, p34, p37
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Antibody Type
Monoclonal
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Clone
1H9-D3-E11
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Species Reactivities
Human
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Immunogen Sequence
Recombinant human Cyclin H protein fragments expressed in E.coli
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Accession
P51946
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Gene Id
902
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
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Purification
Affinity purified
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Application
WB, IP
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Positive Control
WB: Jurkat, K562 and A431 cell lysates; IP: HeLa cell lysates
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Application And Usages
WB; 1:1000, IP
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Description
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
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Storage Condition
-20 °C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans
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Handling
The antibody solution should be gently mixed before use
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Not Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Verified
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FACS Verified
Not Verified
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ELISA Verified
Not Verified
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ChIP Verified
Not Verified
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Dot Blot Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
SNRPD3, NCAPD3, TRO
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Short name
Anti-Cyclin H Antibody (1H9-D3-E11)
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Isotype
Mouse IgG2b
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Alternative name
Antibody toCyclin H (antibody to-) (1H9-D3-E11)
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Alternative technique
antibodies
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Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
trophinin
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Synonyms
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GenBank acession
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Locus
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Discovery year
1997-10-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
- Small nucleolar RNA protein coding host genes
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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