Anti-Angiopoietin-2 Antibody
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Catalog number
A1291-100
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Price
Please ask
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Size
100 µg
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Antibody Target
ANGPT2
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Target Alternative Name
Angiopoietin-2, ANG-2
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Antibody Type
Polyclonal
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Species Reactivities
Human, Mouse, Rat
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Immunogen Sequence
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Angiopoietin-2
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Accession
O15123
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Gene Id
285
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide
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Purification
Affinity purified
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Application
WB
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Positive Control
WB: Hela, Raw264.7, H9C2 whole cell lysate
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Application And Usages
WB; 1:500 – 1:1000
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Description
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
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Storage Condition
-20 °C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans
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Handling
The antibody solution should be gently mixed before use
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Not Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Not Verified
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FACS Verified
Not Verified
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ELISA Verified
Not Verified
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ChIP Verified
Not Verified
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Dot Blot Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
ANGPT2, ANGPTL2, TEK
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Short name
Anti-Angiopoietin-2 Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
Antibody toAngiopoietin-2 (antibody to-)
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
angiopoietin 2
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Synonyms
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GenBank acession
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Locus
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Discovery year
1997-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibrinogen C domain containing
- Receptor ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
angiopoietin like 2
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-02-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Angiopoietin like family
- Fibrinogen C domain containing
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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