Amrinone
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Catalog numberB2465-50
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PricePlease ask
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Size50 mg
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Alternative_name5-amino-[3,4'-bipyridin]-6(1H)-one; WIN 40,680
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DescriptionAmrinone is a potent phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. It also displays positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.
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CAS Number60719-84-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₀H₉N₃O
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Molecular Weight187.2
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Cell PermeableTrue
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Purity≥98% by HPLC
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Solubilities0.5 mg/ml in DMSO
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HandlingDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag LineA phosphodiesterase 3 (PDE3) inhibitor
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Storage Condition-20ºC
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Shipping ConditionGel Pack
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Shelf Life36 months
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MDL NumberMFCD00083228
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PubChem CID3698
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SMILESC1=CN=CC=C1C2=CNC(=O)C(=C2)N
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InChiInChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)
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InChi KeyRNLQIBCLLYYYFJ-UHFFFAOYSA-N
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MSDS AvailableTrue
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Gene target
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Short nameAmrinone
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Alternative nameAmrinone
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