Amrinone

  • Catalog number
    B2465-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    5-amino-[3,4'-bipyridin]-6(1H)-one; WIN 40,680
  • Description
    Amrinone is a potent phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. It also displays positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.
  • CAS Number
    60719-84-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₀H₉N₃O
  • Molecular Weight
    187.2
  • Cell Permeable
    True
  • Purity
    ≥98% by HPLC
  • Solubilities
    0.5 mg/ml in DMSO
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    A phosphodiesterase 3 (PDE3) inhibitor
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00083228
  • PubChem CID
    3698
  • SMILES
    C1=CN=CC=C1C2=CNC(=O)C(=C2)N
  • InChi
    InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)
  • InChi Key
    RNLQIBCLLYYYFJ-UHFFFAOYSA-N
  • MSDS Available
    True
  • Gene target
  • Short name
    Amrinone
  • Alternative name
    Amrinone
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