Amphotericin B, USP
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Catalog number2497-1G
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PricePlease ask
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Size1 g
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Alternative_nameFungizone
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DescriptionA polyene antifungal antibiotic from Streptomyces. Amphotericin B targets a wide range of susceptible fungi including Histoplasma, Coccidioides, and Cryptococcus species. Amphotericin B targets ergosterol in the fungal cell membrane and increases permeability. This alteration of the cell membrane is toxic to the fungus and leads to death. Can be used as a selective agent in several types of isolation media.
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CAS Number1397-89-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₄₇H₇₃NO₁₇
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Molecular Weight924.08
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Cell PermeableNo
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Purity>750 µg/mg
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SolubilitiesDMF (~2-4 mg/ml) or DMSO (~30-40 mg/ml)
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HandlingProtect from air and moisture
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Tag LineAn antibiotic and selection agent
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Storage Condition+4°C
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Shipping ConditionGel pack
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Shelf Life24 months
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MDL NumberMFCD00877763
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PubChem CID5280965
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SMILESCC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O
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InChiInChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
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InChi KeyAPKFDSVGJQXUKY-INPOYWNPSA-N
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MSDS AvailableYes
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Gene target
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Short nameAmphotericin B, USP
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Alternative nameAmphotericin B, USP
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