Amlodipine besylate
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Catalog number2378-50
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PricePlease ask
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Size50 mg
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Alternative_name2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate
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DescriptionA L-type calcium channel blocker and an anti-hypertensive agent. Amlodipine displays vasoprotective effects in cardiovascular disease and inhibits Ca²⁺-induced contractions in depolarized rat aorta (IC₅₀ = 1.9 nM). Amlodipin also inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC₅₀ = 25 μM).
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CAS Number111470-99-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₀H₂₅ClN₂O₅.C₆H₆O₃S
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Molecular Weight567.05
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~100 mM) or H₂O (~10 mM)
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HandlingProtect from light and moisture
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Tag LineA calcium channel blocker
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Storage Condition+4°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD00887594
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PubChem CID60496
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SMILESCCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O
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InChiInChI=1S/C20H25ClN2O5.C6H6O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;7-10(8,9)6-4-2-1-3-5-6/h5-8,17,23H,4,9-11,22H2,1-3H3;1-5H,(H,7,8,9)
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InChi KeyZPBWCRDSRKPIDG-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameAmlodipine besylate
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Alternative nameAmlodipine besylate
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