AMG319

  • Catalog number
    B1663-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    AMG319, AMG319; AMG 319; N-[(1S)-1-(7-fluoro-2-pyridin-2-ylquinolin-3-yl)ethyl]-7H-purin-6-amine; (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine
  • Description
    AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, also inhibits PI3Kγ with IC50 of 850 nM.
  • CAS Number
    1608125-21-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₁H₁₆FN₇
  • Molecular Weight
    385.4
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A highly selective inhibitor of phosphoinositide 3-kinase p110δ isoform
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    68947304
  • SMILES
    CC(C1=C(N=C2C=C(C=CC2=C1)F)C3=CC=CC=N3)NC4=NC=NC5=C4NC=N5
  • InChi
    InChI=1S/C21H16FN7/c1-12(28-21-19-20(25-10-24-19)26-11-27-21)15-8-13-5-6-14(22)9-17(13)29-18(15)16-4-2-3-7-23-16/h2-12H,1H3,(H2,24,25,26,27,28)/t12-/m0/s1
  • InChi Key
    KWRYMZHCQIOOEB-LBPRGKRZSA-N
  • MSDS Available
    Yes
  • Gene target
    AMG319  
  • Short name
    AMG319
  • Alternative name
    AMG319
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