AMG319
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Catalog numberB1663-5
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PricePlease ask
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Size5 mg
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Alternative_nameAMG319, AMG319; AMG 319; N-[(1S)-1-(7-fluoro-2-pyridin-2-ylquinolin-3-yl)ethyl]-7H-purin-6-amine; (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine
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DescriptionAMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, also inhibits PI3Kγ with IC50 of 850 nM.
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CAS Number1608125-21-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₁H₁₆FN₇
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Molecular Weight385.4
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA highly selective inhibitor of phosphoinositide 3-kinase p110δ isoform
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID68947304
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SMILESCC(C1=C(N=C2C=C(C=CC2=C1)F)C3=CC=CC=N3)NC4=NC=NC5=C4NC=N5
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InChiInChI=1S/C21H16FN7/c1-12(28-21-19-20(25-10-24-19)26-11-27-21)15-8-13-5-6-14(22)9-17(13)29-18(15)16-4-2-3-7-23-16/h2-12H,1H3,(H2,24,25,26,27,28)/t12-/m0/s1
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InChi KeyKWRYMZHCQIOOEB-LBPRGKRZSA-N
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MSDS AvailableYes
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Gene target
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Short nameAMG319
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Alternative nameAMG319
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