Alpha 1 Acid Glycoprotein, Human Plasma
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Catalog number
7547-2
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Price
Please ask
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Size
2 mg
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Synonyms
AGP, Orosomucoid
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Alternative_names
AGP, Orosomucoid
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Description
An acute-phase reactant that together with haptoglobin is an indicator of acute inflammation.
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Recombinant
No
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Source
Human Plasma
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Biological activity
≥ 120 units/mg protein. One unit is defined as the amount of enzyme which will hydrolyze 1 µmole of N-tosyl-L-arginine methyl ester in 30 minutes at 37°C at pH 8.0.
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Results
≥ 120 units/mg protein.
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Unit Definition
One unit is defined as the amount of enzyme which will hydrolyze 1 µmole of N-tosyl-L-arginine methyl ester in 30 minutes at 37°C at pH 8.0.
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Molecular Weight
40.0 kDa
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized
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Physical form description
Lyophilized as a salt free solid.
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Background Information
Found in human plasma in concentrations of 55-140 mg per 100 ml. Classical standard glycoprotein for studies on the structure of the oligosaccharide units. Carbohydrate content is 40%. Its biological significance is unknown although it can bind progesterone 15 times as strongly as albumin. Sialic-acid-deficient alpha-1-AG has an affinity for vitamin B-12. Clinically, alpha 1 acid glycoprotein is an acute-phase reactant that together with haptoglobin is an indicator of acute inflammation. The alpha 1 acid glycoprotein: haptoglobin ratio is useful in studies of bone marrow disorders, hemolytic processes and metastases.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Additional description
The Alpha 1 Acid Glycoprotein, Plasma is a α- or alpha protein sometimes glycoprotein present in blood.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Short name
Alpha 1 Acid Glycoprotein, Plasma
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Species
Human, Humans
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Alternative name
a 1 Acid Glycoprotein, H. sapiens Plasma
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Product images
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