Alendronate sodium

  • Catalog number
    2168-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    Sodium [4-amino-1-hydroxy-1-(hydroxy-oxido-phosphoryl)- butyl]phosphonic acid, trihydrate; MK-217; Fosamax
  • Description
    Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. It inhibits bone resorption in vitro with an IC₅₀ value of 2 nM. Also acts as a farnesyl diphosphate synthase inhibitor (IC₅₀ = 460 nM) and CD45 protein tyrosine phosphatase inhibitor.
  • CAS Number
    121268-17-5
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₄H₁₂NaNO₇P₂ · 3 H₂O
  • Molecular Weight
    325.12
  • Cell Permeable
    No
  • Purity
    ≥95%
  • Solubilities
    H₂O (10 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A specific inhibitor of osteoclast-mediated bone resorption
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • MDL Number
    MFCD01748233
  • PubChem CID
    23681107
  • SMILES
    C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+]
  • InChi
    InChI=1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
  • InChi Key
    DCSBSVSZJRSITC-UHFFFAOYSA-M
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Alendronate sodium
  • Alternative name
    Alendronate sodium
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