AIF Antibody

• Catalog number
  3202-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  AIF
• Target Alternative Name
  AIFM1, PDCD8, mgC111425
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 520 of human AIF
• Accession
  O95831
• Gene Id
  9131
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) affinity purified rabbit anti-AIF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). A ~67 kDa band should be detected. Jurkat cell lysate can be used as a positive control. However, the optimal conditions for your testing samples should be determined individually.
• Description
  AIF (apoptosis inducing factor) was recently identified that causes chromatin condensation and DNA fragmentation. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and DNA fragmentation, which are the hallmarks of apoptosis. AIF is highly conserved between human and mouse and widely expressed.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AIF  
• Gene symbol
  AIF1, AIFM1
• Short name
  AIF Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  AIF (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:352
• Gene
  AIF1
• Long gene name
  allograft inflammatory factor 1
• Synonyms
  • IRT-1
  • AIF-1
  • Em:AF129756.17
  • IBA1
• Synonyms name
  • interferon gamma responsive transcript
  • ionized calcium-binding adapter molecule 1
• GenBank acession
  • U19713
• Locus
  6p21.33
• Discovery year
  1997-07-01
• Entrez gene record
  199
• Pubmed identfication
  • 8912632
• Classification
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000031246

Gene info

• Identity
  HGNC:8768
• Gene
  AIFM1
• Long gene name
  apoptosis inducing factor mitochondria associated 1
• Synonyms gene
  • PDCD8
  • NAMSD
  • AUNX1
• Synonyms gene name
  • programmed cell death 8 (apoptosis-inducing factor)
  • neuropathy, axonal, motor-sensory with deafness and mental retardation (Cowchock syndrome)
  • apoptosis-inducing factor, mitochondrion-associated, 1
  • apoptosis inducing factor, mitochondria associated 1
  • auditory neuropathy, X-linked recessive 1
• Synonyms
  • AIF
  • CMTX4
  • DFNX5
• GenBank acession
  • AF100928
• Locus
  Xq26.1
• Discovery year
  1999-05-28
• Entrez gene record
  9131
• Pubmed identfication
  • 9989411
  • 23217327
  • 25986071
• VEGA ID
  OTTHUMG00000022392
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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