Adaphostin

• Catalog number
  B2787-25
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  AG 957 Adamantyl Ester,NSC-680410,4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[3.3.1.13,7]dec-1-yl ester
• Description
  Adaphostin is a p210bcr/abl tyrosine kinase inhibitor (IC50 = 14 μM) that displays anti-proliferative activity in leukemia models, human prostate cancer cell line PC-3 and other cancer cell lines. Adaphostin is a potent inducer of myeloid cell death.
• CAS Number
  241127-58-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₂₇NO₄
• Molecular Weight
  393.48
• Cell Permeable
  1
• Purity
  ≥98% by HPLC
• Solubilities
  >30 mg/ml Ethanol, >30 mg/ml DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A p210bcr/abl kinase inhibitor
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD06411386
• PubChem CID
  387042
• PubChem CID Link
• SMILES
  C1C2CC3CC1CC(C2)(C3)OC(=O)C4=CC=C(C=C4)NCC5=C(C=CC(=C5)O)O
• InChi
  InChI=1S/C24H27NO4/c26-21-5-6-22(27)19(10-21)14-25-20-3-1-18(2-4-20)23(28)29-24-11-15-7-16(12-24)9-17(8-15)13-24/h1-6,10,15-17,25-27H,7-9,11-14H2
• InChi Key
  YJZSUCFGHXQWDM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  1

• Gene target
  Adaphostin  
• Short name
  Adaphostin
• Alternative name
  Adaphostin

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