ACT-129968
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Catalog numberB2316-50
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PricePlease ask
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Size50 mg
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Alternative_nameSetipiprant,2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)acetic acid
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DescriptionA potent and selective CRTh2 antagonist. CRTh2 is a G-protein-coupled receptor for prostaglandin D2 (PGD2), a key mediator in inflammatory disorders.
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CAS Number866460-33-5
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Structure AvailableYes
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Molecular FormulaC₂₄H₁₉FN₂O₃
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Molecular Weight402.43
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Purity≥98% by HPLC
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Solubilities>30 mg/ml
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HandlingDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag LineApotent and selective CRTh2 antagonist
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Storage Condition-20ºC
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID49843471
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SMILESC1CN(CC2=C1N(C3=C2C=C(C=C3)F)CC(=O)O)C(=O)C4=CC=CC5=CC=CC=C54
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InChiInChI=1S/C24H19FN2O3/c25-16-8-9-21-19(12-16)20-13-26(11-10-22(20)27(21)14-23(28)29)24(30)18-7-3-5-15-4-1-2-6-17(15)18/h1-9,12H,10-11,13-14H2,(H,28,29)
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InChi KeyIHAXLPDVOWLUOS-UHFFFAOYSA-N
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Gene target
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Gene symbolSERPINA3, POTEM, FHL5, CISTR, ACOT7, CCL4, TRS-ACT1-1
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Short nameACT-129968
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Alternative nameACT-129968
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Gene info
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Identity
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Gene
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Long gene nameserpin family A member 3
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Synonyms gene
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Synonyms gene name
- alpha-1-antichymotrypsin
- serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
- serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Serpin peptidase inhibitors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePOTE ankyrin domain family member M
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Synonyms gene name
- POTE ankyrin domain family, member M
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Synonyms
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Synonyms name
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Locus
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Discovery year2009-06-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- POTE ankyrin domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefour and a half LIM domains 5
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-11-26
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Entrez gene record
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RefSeq identity
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Classification
- LIM domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namechondrogenesis-associated transcript
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2014-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Long non-coding RNAs with non-systematic symbols
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameacyl-CoA thioesterase 7
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Acyl-CoA thioesterases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine ligand 4
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Synonyms gene
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Synonyms gene name
- small inducible cytokine A4 (homologous to mouse Mip-1b)
- chemokine (C-C motif) ligand 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-07-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametRNA-Ser (anticodon ACT) 1-1
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Synonyms gene
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Synonyms gene name
- transfer RNA serine 32 (anticodon ACU) pseudogene
- transfer RNA-Ser (ACT) 1-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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RefSeq identity
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Classification
- Cytoplasmic transfer RNA pseudogenes