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Alternative_name
7-Iodo-7-deazaadenosine 4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine NSC-113939 5-Iodotubericidin NSC113939
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Description
5-Iodotubercidin is a potent adenosine kinase inhibitor (IC₅₀ = 26 nM). 5-Iodotubercidin initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin also acts as an activator for p53 and favors tumor suppression and may serve as a potential chemotherapeutic agent.
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CAS Number
24386-93-4
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Structure Available
1
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Molecular Formula
C₁₁H₁₃IN₄O₄
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Molecular Weight
392.15
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Cell Permeable
1
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Purity
≥90% by HPLC
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Solubilities
>15 mg/ml DMSO
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Handling
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag Line
A potent adenosine kinase inhibitor
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Storage Condition
-20ºC
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Shipping Condition
Gel Pack
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Shelf Life
36months
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MDL Number
MFCD00055131
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PubChem CID
97297
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SMILES
O[C@H]([C@H](O)[C@@H](CO)O3)[C@@H]3N1C2=C(C(N)=NC=N2)C(I)=C1
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InChi
InChI=1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1
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InChi Key
WHSIXKUPQCKWBY-IOSLPCCCSA-N
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MSDS Available
1