5-Iodotubercidin

  • Catalog number
    B2721-10
  • Price
    Please ask
  • Size
    10 mg
  • Alternative_name
    7-Iodo-7-deazaadenosine 4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine NSC-113939 5-Iodotubericidin NSC113939
  • Description
    5-Iodotubercidin is a potent adenosine kinase inhibitor (IC₅₀ = 26 nM). 5-Iodotubercidin initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin also acts as an activator for p53 and favors tumor suppression and may serve as a potential chemotherapeutic agent.
  • CAS Number
    24386-93-4
  • Structure Available
    1
  • Molecular Formula
    C₁₁H₁₃IN₄O₄
  • Molecular Weight
    392.15
  • Cell Permeable
    1
  • Purity
    ≥90% by HPLC
  • Solubilities
    >15 mg/ml DMSO
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    A potent adenosine kinase inhibitor
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36months
  • MDL Number
    MFCD00055131
  • PubChem CID
    97297
  • SMILES
    O[C@H]([C@H](O)[C@@H](CO)O3)[C@@H]3N1C2=C(C(N)=NC=N2)C(I)=C1
  • InChi
    InChI=1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1
  • InChi Key
    WHSIXKUPQCKWBY-IOSLPCCCSA-N
  • MSDS Available
    1
  • Gene target
  • Short name
    5-Iodotubercidin
  • Alternative name
    5-Iodotubercidin
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