ZEB Antibody

• Catalog number
  bs-4187R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ZEB Primary Polyclonal Antibody
• Also known as
  ZEB PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Zinc finger E-box-binding homeobox 1 & 2
• Specificity
  This is a highly specific antibody against Zinc finger E-box-binding homeobox 1 & 2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  210-260/1124
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZEB1
• Gene ID number
  6935, 9839
• Tested Applications
  WB, FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Inhibits interleukin-2 (IL-2) gene expression. May be responsible for transcriptional repression of the IL-2 gene. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  AREB 6; AREB6; BZP; Delta crystallin enhancer binding factor 1; DELTA EF1; FECD6; MGC133261; Negative regulator of IL 2; Negative regulator of IL2; NIL 2 A; NIL 2 A zinc finger protein; NIL 2A; NIL-2-A zinc finger protein; NIL2A; Posterior polymorphous corneal dystrophy 3; PPCD3; Represses interleukin 2 expression; TCF 8; TCF-8; TCF8; Transcription factor 8 represses interleukin 2 expression; Transcription factor 8; ZEB 1; ZEB; ZEB1; ZEB1_HUMAN; ZFHEP; ZFHX 1A; ZFHX1A; Zinc finger E box binding homeobox 1; Zinc finger E-box-binding homeobox 1; Zinc finger homeodomain enhancer binding protein.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ZEB  
• Gene symbol
  ZEB1
• Short name
  Anti-Zinc finger E-box-binding homeobox 1 & 2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ZEB Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11642
• Gene
  ZEB1
• Long gene name
  zinc finger E-box binding homeobox 1
• Synonyms gene
  • TCF8
  • PPCD3
• Synonyms gene name
  • transcription factor 8 (represses interleukin 2 expression)
  • posterior polymorphous corneal dystrophy 3
• Synonyms
  • BZP
  • ZEB
  • AREB6
  • NIL-2-A
  • Zfhep
  • Zfhx1a
  • FECD6
• GenBank acession
  • AK091478
• Locus
  10p11.22
• Discovery year
  1991-12-17
• Entrez gene record
  6935
• Pubmed identfication
  • 1427828
  • 1840704
  • 15384081
  • 16252232
• RefSeq identity
  • NM_030751
• Classification
  • ZF class homeoboxes and pseudogenes
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000017907

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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