YB1 Antibody

• Catalog number
  bs-1943R
• Price
  Please ask
• Size
  0.1ml

• Long name
  YB1 Primary Polyclonal Antibody
• Also known as
  YB1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  YB1
• Specificity
  This is a highly specific antibody against YB1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  120-170/324
• Subcellular location
  Cytoplasm, Nucleus, Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human YBX-1
• Gene ID number
  4904
• Swiss Prot
  P67809
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  YB1; BP-8; CSDB; DBPB; YB-1; CSDA2; NSEP1; NSEP-1; MDR-NF1; Nuclease-sensitive element-binding protein 1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1; YBX1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  YB1  
• Gene symbol
  YBX1
• Short name
  Anti-YB1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  YB1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8014
• Gene
  YBX1
• Long gene name
  Y-box binding protein 1
• Synonyms gene
  • NSEP1
• Synonyms gene name
  • nuclease sensitive element binding protein 1
• Synonyms
  • YB-1
  • YB1
  • DBPB
  • NSEP-1
  • MDR-NF1
  • BP-8
  • CSDB
  • CSDA2
• GenBank acession
  • BC013838
• Locus
  1p34.2
• Discovery year
  1993-10-20
• Entrez gene record
  4904
• Pubmed identfication
  • 1891370
  • 3174636
  • 29478751
• RefSeq identity
  • NM_004559
• Classification
  • Y-box binding proteins
  • U11 small nuclear ribonucleoprotein
  • U11/U12 di-snRNP
• VEGA ID
  OTTHUMG00000007523

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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