VAV2 Antibody

• Catalog number
  bs-6160R
• Price
  Please ask
• Size
  0.1ml

• Long name
  VAV2 Primary Polyclonal Antibody
• Also known as
  VAV2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  VAV2
• Specificity
  This is a highly specific antibody against VAV2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human VAV2
• Gene ID number
  7410
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Oncogene VAV2; Protein vav 2; VAV 2; Vav 2 oncogene; VAV2 oncogene; VAV2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  VAV2  
• Gene symbol
  VAV2
• Short name
  Anti-VAV2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  VAV2 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  vav 2 guanine nucleotide exchange factor, VAV-2, VAV2 and IDBG-91583 and ENSG00000160293 and 7410, metal ion binding, Plasma membranes, Vav2 and IDBG-151026 and ENSMUSG00000009621 and 22325, VAV2 and IDBG-640833 and ENSBTAG00000004511 and 515718

Gene info

• Identity
  HGNC:12658
• Gene
  VAV2
• Long gene name
  vav guanine nucleotide exchange factor 2
• Synonyms gene name
  • vav 2 oncogene
  • vav 2 guanine nucleotide exchange factor
• Locus
  9q34.2
• Discovery year
  1994-07-15
• Entrez gene record
  7410
• Pubmed identfication
  • 7762982
• Classification
  • Pleckstrin homology domain containing
  • SH2 domain containing
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000020882

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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