USP5 (1340CT704.170.140) Monoclonal Antibody

• Catalog number
  bsm-51404M
• Price
  Please ask
• Size
  0.1ml

• Long name
  USP5 (1340CT704.170.140) Monoclonal Antibody
• Also known as
  USP5 (1340CT704.170.140) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  USP5
• Specificity
  This is a highly specific antibody against USP5.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  1340CT704.170.140
• Source
  This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5.
• Gene ID number
  8078
• Swiss Prot
  P45974
• Tested Applications
  WB
• Recommended dilutions
  WB(1:1000)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
• Purification method
  Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ISOT; Ubiquitin carboxyl-terminal hydrolase 5; Deubiquitinating enzyme 5; Isopeptidase T; Ubiquitin thioesterase 5; Ubiquitin-specific-processing protease 5; USP5
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  USP5   1340CT704   170   140   Monoclonal  
• Gene symbol
  USP5
• Short name
  Anti-USP5
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)1 κ
• Alternative name
  USP5 (1340CT704.170.140) Monoclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12628
• Gene
  USP5
• Long gene name
  ubiquitin specific peptidase 5
• Synonyms gene name
  • ubiquitin specific peptidase 5 (isopeptidase T)
• Synonyms
  • IsoT
• Synonyms name
  • isopeptidase T
• GenBank acession
  • U35116
• Locus
  12p13
• Discovery year
  1999-02-01
• Pubmed identfication
  • 12838346
  • 8723724
• Classification
  • Ubiquitin specific peptidases
• VEGA ID
  OTTHUMG00000169233

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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