UCHL3 Antibody

• Catalog number
  bs-11676R
• Price
  Please ask
• Size
  0.1ml

• Long name
  UCHL3 Primary Polyclonal Antibody
• Also known as
  UCHL3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  UCHL3
• Specificity
  This is a highly specific antibody against UCHL3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  130-180/230
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UCHL3
• Gene ID number
  7347
• Swiss Prot
  P15374
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1 to 2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p14. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Ubiquitin carboxyl-terminal hydrolase isozyme L3; Ubiquitin thioesterase L3; Ubiquitin thiolesterase; Ubiquitin thiolesterase L3; UCH L3; UCH-L3; UCHL3; UCHL3_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  UCHL3  
• Gene symbol
  UCHL3, LMO7-AS1
• Short name
  Anti-UCHL3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  UCHL3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12515
• Gene
  UCHL3
• Long gene name
  ubiquitin C-terminal hydrolase L3
• Synonyms gene name
  • ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
• Synonyms name
  • ubiquitin thiolesterase
• GenBank acession
  • M30496
• Locus
  13q22.2
• Discovery year
  1991-07-15
• Entrez gene record
  7347
• Pubmed identfication
  • 2530630
• RefSeq identity
  • NM_006002
• Classification
  • Ubiquitin C-terminal hydrolases
• VEGA ID
  OTTHUMG00000017090

Gene info

• Identity
  HGNC:50277
• Gene
  LMO7-AS1
• Long gene name
  LMO7 antisense RNA 1
• Synonyms
  • UCHL3-AS1
• Synonyms name
  • UCHL3 antisense RNA 1
• GenBank acession
  • AW188034
• Locus
  13q22.2
• Discovery year
  2014-03-25
• Entrez gene record
  101927155
• RefSeq identity
  • NR_120410
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000172803

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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