UBR2 Antibody

• Catalog number
  bs-9144R
• Price
  Please ask
• Size
  0.1ml

• Long name
  UBR2 Primary Polyclonal Antibody
• Also known as
  UBR2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  UBR2
• Specificity
  This is a highly specific antibody against UBR2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UBR2
• Gene ID number
  23304
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  E3 ubiquitin protein ligase UBR2; N recognin 2; Ubiquitin ligase E3 alpha II; Ubiquitin protein ligase E3 alpha 2; Ubiquitin protein ligase E3 component n recognin 2; UBR 2; UBR2_HUMAN; N-recognin-2; Ubiquitin-protein ligase E3-alpha-2; Ubiquitin-protein ligase E3-alpha-II.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  UBR2  
• Gene symbol
  UBR2
• Short name
  Anti-UBR2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  UBR2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:21289
• Gene
  UBR2
• Long gene name
  ubiquitin protein ligase E3 component n-recognin 2
• Synonyms gene
  • C6orf133
• Synonyms gene name
  • chromosome 6 open reading frame 133
• Synonyms
  • bA49A4.1
  • dJ392M17.3
  • KIAA0349
• GenBank acession
  • BC024217
• Locus
  6p21.1
• Discovery year
  2003-11-26
• Entrez gene record
  23304
• RefSeq identity
  • NM_015255
• Classification
  • Ubiquitin protein ligase E3 component n-recognins
• VEGA ID
  OTTHUMG00000014703

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products