Ubiquitin D Antibody

• Catalog number
  bs-13006R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Ubiquitin D Primary Polyclonal Antibody
• Also known as
  Ubiquitin D PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Ubiquitin D
• Specificity
  This is a highly specific antibody against Ubiquitin D.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  60-100/165
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ubiquitin D
• Gene ID number
  10537
• Swiss Prot
  O15205
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1L-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs). May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle. May be involved in the formation of aggresomes when proteasome is saturated or impaired. Mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  FAT10; UBD-3; GABBR1; Ubiquitin D; Diubiquitin; Ubiquitin-like protein FAT10; UBD
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Ubiquitin  
• Gene symbol
  UBD, UBDP1, UBE2DNL
• Short name
  Anti-Ubiquitin D
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Ubiquitin D Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18795
• Gene
  UBD
• Long gene name
  ubiquitin D
• Synonyms
  • FAT10
• GenBank acession
  • Y12653
• Locus
  6p22.1
• Discovery year
  2002-06-19
• Entrez gene record
  10537
• Pubmed identfication
  • 9368598
  • 8662070
• VEGA ID
  OTTHUMG00000031289

Gene info

• Identity
  HGNC:18796
• Gene
  UBDP1
• Long gene name
  ubiquitin D pseudogene 1
• Synonyms
  • dJ994E9.3
• Locus
  6p22.1
• Discovery year
  2003-11-27
• Entrez gene record
  100286971
• VEGA ID
  OTTHUMG00000031258

Gene info

• Identity
  HGNC:28656
• Gene
  UBE2DNL
• Long gene name
  ubiquitin conjugating enzyme E2 D N-terminal like (pseudogene)
• Synonyms gene name
  • ubiquitin-conjugating enzyme E2D N-terminal like
  • ubiquitin-conjugating enzyme E2D N-terminal like pseudogene
  • ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene)
• Synonyms
  • MGC42638
• GenBank acession
  • BC040290
• Locus
  Xq21.1
• Discovery year
  2006-12-11
• Entrez gene record
  100131816
• Pubmed identfication
  • 12477932
• RefSeq identity
  • NR_024062
• VEGA ID
  OTTHUMG00000021928

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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