TWIST protein Antibody

• Catalog number
  bs-2441R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TWIST protein Primary Polyclonal Antibody
• Also known as
  TWIST protein PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TWIST
• Specificity
  This is a highly specific antibody against TWIST.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  108-150/202
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TWIST
• Gene ID number
  7291
• Swiss Prot
  Q15672
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CRS; SCS; ACS3; CRS1; BPES2; BPES3; TWIST; bHLHa38; Twist-related protein 1; Class A basic helix-loop-helix protein 38; H-twist; TWIST1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TWIST   protein  
• Gene symbol
  TWIST1, FERD3L
• Short name
  Anti-TWIST
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TWIST protein Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12428
• Gene
  TWIST1
• Long gene name
  twist family bHLH transcription factor 1
• Synonyms gene
  • ACS3
  • BPES3
  • TWIST
  • CRS
• Synonyms gene name
  • blepharophimosis, epicanthus inversus and ptosis 3
  • acrocephalosyndactyly 3
  • twist homolog 1 (Drosophila)
  • twist basic helix-loop-helix transcription factor 1
  • craniosynostosis
• Synonyms
  • SCS
  • H-twist
  • BPES2
  • bHLHa38
  • CRS1
• Synonyms name
  • Saethre-Chotzen syndrome
• GenBank acession
  • U80998
• Locus
  7p21.1
• Discovery year
  1997-07-01
• Entrez gene record
  7291
• Pubmed identfication
  • 8995765
  • 11474656
  • 17343269
• RefSeq identity
  • NM_000474
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000090821

Gene info

• Identity
  HGNC:16660
• Gene
  FERD3L
• Long gene name
  Fer3 like bHLH transcription factor
• Synonyms gene name
  • Fer3-like (Drosophila)
  • Fer3-like bHLH transcription factor
• Synonyms
  • NATO3
  • N-TWIST
  • bHLHa31
• GenBank acession
  • AF369897
• Locus
  7p21.1
• Discovery year
  2002-12-09
• Entrez gene record
  222894
• Pubmed identfication
  • 11472856
  • 12217327
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000090823

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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