TTBK2/SCA11 Antibody

• Catalog number
  bs-11771R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TTBK2/SCA11 Primary Polyclonal Antibody
• Also known as
  TTBK2/SCA11 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TTBK2/SCA11
• Specificity
  This is a highly specific antibody against TTBK2/SCA11.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TTBK2/SCA11
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  SCA11 is a 1,244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3,732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TTBK2/SCA11 Tau tubulin kinase 2; Spinocerebellar ataxia 11; Tau tubulin kinase 2; Tau-tubulin kinase 2; TTBK; TTBK 2; TTBK1; TTBK2 ; TTBK2_HUMAN; TTK; KIAA0847; mKIAA0847; SCA11.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TTBK2/SCA11  
• Gene symbol
  TTBK2, TTBK2-AS1
• Short name
  Anti-TTBK2/SCA11
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TTBK2/SCA11 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19141
• Gene
  TTBK2
• Long gene name
  tau tubulin kinase 2
• Synonyms gene
  • SCA11
• Synonyms gene name
  • spinocerebellar ataxia 11
• Synonyms
  • KIAA0847
• GenBank acession
  • AB020654
• Locus
  15q15.2
• Discovery year
  2003-05-28
• Entrez gene record
  146057
• Pubmed identfication
  • 10048485
• RefSeq identity
  • NM_173500
• VEGA ID
  OTTHUMG00000175802

Gene info

• Identity
  HGNC:55598
• Gene
  TTBK2-AS1
• Long gene name
  TTBK2 antisense RNA 1
• Locus
  15q15.2
• Discovery year
  2021-04-30
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products