TRRAP Antibody

• Catalog number
  bs-13146R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TRRAP Primary Polyclonal Antibody
• Also known as
  TRRAP PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TRRAP
• Specificity
  This is a highly specific antibody against TRRAP.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRRAP
• Gene ID number
  8295
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The transcription factors c-Myc and E2F are involved in regulating cell cycle progression. Overexpression of c-Myc in certain cell types induces noncycling cells to enter the cell cycle via a mechanism involving E2F-1 (1). E2F-1 is thought to regulate c-Myc expression via interactions with the retinoblastoma protein (2). TRRAP (for transformation/transcription domain-associated protein) interacts specifically with both c-Myc and E2F-1. Expression of trans-activated mutant TRRAP inhibits the oncogenic transformation of both c-Myc and E2F-1, suggesting that TRRAP is required for these oncogenic transcription factor pathways (3). TRRAP shares homology with the ATM/PI 3-kinase family, and it is highly conserved in evolution (4,5).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  350/400 kDa PCAF associated factor; FLJ10671; PAF 350/400; PAF 400; PAF350/400; PAF400; STAF 40; STAF40; TR AP; Tra 1; Tra1; Tra1 homolog; Transactivation / transformation domain associated protein; Transactivation/transformation domain associated protein; Transformation/transcription domain associated protein; TRAP; TRRAP_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRRAP  
• Gene symbol
  TRRAP
• Short name
  Anti-TRRAP
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TRRAP Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12347
• Gene
  TRRAP
• Long gene name
  transformation/transcription domain associated protein
• Synonyms gene name
  • transformation/transcription domain-associated protein
• Synonyms
  • TR-AP
  • PAF400
  • Tra1
• GenBank acession
  • AF076974
• Locus
  7q22.1
• Discovery year
  1998-10-06
• Entrez gene record
  8295
• Pubmed identfication
  • 9708738
  • 9885574
• RefSeq identity
  • NM_003496
• Classification
  • MicroRNA protein coding host genes
  • SAGA complex
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000150403

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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