TRADD Antibody

• Catalog number
  bs-1202R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TRADD Primary Polyclonal Antibody
• Also known as
  TRADD PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TRADD
• Specificity
  This is a highly specific antibody against TRADD.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  120-170/310
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic peptide derived from mouse of mouse TRADD
• Gene ID number
  71609
• Swiss Prot
  Q3U0V2
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  AA930854; 9130005N23Rik; Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain; Tradd
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRADD  
• Gene symbol
  TRADD
• Short name
  Anti-TRADD
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TRADD Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  TNFRSF1A-associated via death domain, Hs.89862, TRADD and IDBG-36010 and ENSG00000102871 and 8717, binding, nuclei, Tradd and IDBG-186918 and ENSMUSG00000031887 and 71609, TRADD and IDBG-633302 and ENSBTAG00000012642 and 504707

Gene info

• Identity
  HGNC:12030
• Gene
  TRADD
• Long gene name
  TNFRSF1A associated via death domain
• Synonyms gene name
  • TNFRSF1A-associated via death domain
• Synonyms
  • Hs.89862
• GenBank acession
  • L41690
• Locus
  16q22.1
• Discovery year
  1999-05-07
• Entrez gene record
  8717
• Pubmed identfication
  • 7758105
  • 22333735
• VEGA ID
  OTTHUMG00000137519

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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