TMEM2L Antibody

• Catalog number
  bs-8059R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TMEM2L Primary Polyclonal Antibody
• Also known as
  TMEM2L PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TMEM2L
• Specificity
  This is a highly specific antibody against TMEM2L.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  140-177/1361
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TMEM2L
• Gene ID number
  57214
• Swiss Prot
  Q8WUJ3
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CCSP1; TMEM2L; KIAA1199; Cell migration-inducing and hyaluronan-binding protein; CEMIP
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TMEM2L  
• Gene symbol
  CEMIP
• Short name
  Anti-TMEM2L
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TMEM2L Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29213
• Gene
  CEMIP
• Long gene name
  cell migration inducing hyaluronidase 1
• Synonyms gene
  • KIAA1199
• Synonyms gene name
  • KIAA1199
  • cell migration inducing protein, hyaluronan binding
  • cell migration inducing hyaluronan binding protein
• Synonyms
  • IR2155535
  • TMEM2L
  • HYBID
• Synonyms name
  • hyaluronan-binding protein involved in hyaluronan depolymerization
• GenBank acession
  • BC020256
• Locus
  15q25.1
• Discovery year
  2004-06-29
• Entrez gene record
  57214
• Pubmed identfication
  • 14577002
  • 16157444
  • 24573670
• RefSeq identity
  • NM_018689
• Classification
  • Hyaluronidases
• VEGA ID
  OTTHUMG00000144184

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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