TMEM16C/Anoctamin 3 Antibody

• Catalog number
  bs-12479R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TMEM16C/Anoctamin 3 Primary Polyclonal Antibody
• Also known as
  TMEM16C/Anoctamin 3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TMEM16C/Anoctamin 3
• Specificity
  This is a highly specific antibody against TMEM16C/Anoctamin 3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TMEM16C/Anoctamin 3
• Gene ID number
  63982
• Tested Applications
  WB, FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ANO3; C11orf25; GENX 3947; TMEM16C; Transmembrane protein 16C eight membrane spanning domains; Transmembrane protein 16C; ANO3_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TMEM16C/Anoctamin  
• Gene symbol
  ANO3
• Short name
  Anti-TMEM16C/Anoctamin 3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TMEM16C/Anoctamin 3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14004
• Gene
  ANO3
• Long gene name
  anoctamin 3
• Synonyms gene
  • C11orf25
  • TMEM16C
• Synonyms gene name
  • chromosome 11 open reading frame 25
  • transmembrane protein 16C
• Synonyms
  • GENX-3947
  • DYT23
• Synonyms name
  • transmembrane protein 16C (eight membrane-spanning domains)
  • dystonia 23
• GenBank acession
  • AJ300461
• Locus
  11p14.2
• Discovery year
  2000-11-28
• Entrez gene record
  63982
• Pubmed identfication
  • 12739008
  • 15067359
  • 23200863
  • 24692353
• RefSeq identity
  • NM_031418
• Classification
  • Anoctamins
• VEGA ID
  OTTHUMG00000166096

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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