Thioredoxin 2 Antibody

• Catalog number
  bs-4256R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Thioredoxin 2 Primary Polyclonal Antibody
• Also known as
  Thioredoxin 2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Thioredoxin 2
• Specificity
  This is a highly specific antibody against Thioredoxin 2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Thioredoxin 2
• Gene ID number
  25828
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  mitochondrial thioredoxin; MT-TRX; MTRX; thioredoxin 2 precursor; Thioredoxin mitochondrial; Thioredoxin2; TRX 2; TRX2; TXN 2; TXN2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Thioredoxin  
• Gene symbol
  TXNDC2, TMX2P1, TMX2
• Short name
  Anti-Thioredoxin 2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Thioredoxin 2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16470
• Gene
  TXNDC2
• Long gene name
  thioredoxin domain containing 2
• Synonyms gene name
  • thioredoxin domain containing 2 (spermatozoa)
• Synonyms
  • SPTRX1
• Synonyms name
  • sperm-specific thioredoxin 1
• GenBank acession
  • AF080095
• Locus
  18p11.31-p11.2
• Discovery year
  2001-08-30
• Entrez gene record
  84203
• Pubmed identfication
  • 11230166
  • 11399755
• RefSeq identity
  • NM_032243
• Classification
  • Thioredoxin domain containing
• VEGA ID
  OTTHUMG00000131602

Gene info

• Identity
  HGNC:49916
• Gene
  TMX2P1
• Long gene name
  thioredoxin related transmembrane protein 2 pseudogene 1
• Synonyms gene name
  • thioredoxin-related transmembrane protein 2 pseudogene 1
• Locus
  9p13.2
• Discovery year
  2014-03-21
• Entrez gene record
  100233198
• RefSeq identity
  • NG_009211
• VEGA ID
  OTTHUMG00000019929

Gene info

• Identity
  HGNC:30739
• Gene
  TMX2
• Long gene name
  thioredoxin related transmembrane protein 2
• Synonyms gene
  • TXNDC14
• Synonyms gene name
  • thioredoxin domain containing 14
  • thioredoxin-related transmembrane protein 2
• Synonyms
  • PDIA12
• Synonyms name
  • protein disulfide isomerase family A, member 12
• GenBank acession
  • AF132965
• Locus
  11q12.1
• Discovery year
  2005-10-04
• Entrez gene record
  51075
• Pubmed identfication
  • 12670024
• RefSeq identity
  • NM_015959
• Classification
  • Thioredoxin domain containing
  • Protein disulfide isomerases
• VEGA ID
  OTTHUMG00000167200

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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