Thioredoxin 1 (3A1) Monoclonal Antibody
#
-
Catalog numberbsm-50137M
-
Price:
-
Size0.1ml
-
-
Long nameThioredoxin 1 (3A1) Monoclonal Antibody
-
Also known asThioredoxin 1 (3A1) Monoclonal Antibody
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenThioredoxin 1
-
SpecificityThis is a highly specific antibody against Thioredoxin 1.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityMonoclonal
-
Clone number3A1
-
Concentration1ug per 1ul
-
SourceRecombinant human protein purified from E.coli
-
Gene ID number7295
-
Swiss ProtP10599
-
Tested ApplicationsWB, IHC-P, IP
-
Recommended dilutionsWB (1:2000) IP IHC-P
-
Cross reactivityHuman
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenParticipates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
-
Purification methodPurified by Protein G.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesTRX; TRDX; TRX1; Thioredoxin; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP; TXN
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
French translationanticorps
-
Gene target
-
Short nameAnti-Thioredoxin 1
-
TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
-
HostMouse (Mus musculus)
-
IsotypeImmunoglobulin G (IgG)2b κ
-
Alternative nameThioredoxin 1 (3A1) Monoclonal Antibody
-
Alternative techniqueantibodies
-
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data