STXBP1(Ser515) Antibody
-
Catalog numberbs-5639R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameSTXBP1(Ser515) Primary Polyclonal Antibody
-
Also known asSTXBP1(Ser515) PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenSTXBP1 Ser515
-
SpecificityThis is a highly specific antibody against STXBP1 Ser515.
-
Modification sPhosphorylation
-
Modification site sSer515
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic phosphopeptide derived from human STXBP1 around the phosphorylation site of Ser515
-
Gene ID number6812
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenMunc18 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Munc18 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions. Mutations in Munc18 can result in accumulations of acetylcholine and paralytic phenotype suggestive of a neurotransmitter release defect. Two Munc18 isoforms have recently been identified. Munc18-1 has been shown to be primarily expressed in brain, while Munc18-2 is expressed in most tissues.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesStxbp1phospho S515; FLJ37475; hUNC 18; hUNC18; Munc 18 1; Munc 18; Munc 18a; Munc18 1; Munc18a; N Sec1; N-Sec1; Neuronal SEC1; NSec1; p67; Protein unc-18 homolog 1; Protein unc-18 homolog A; Rb sec1; RBSEC1; STX BP1; STXB1_HUMAN; STXBP 1; STXBP1; Syntaxin binding protein 1; Syntaxin-binding protein 1; Unc 18 1; UNC 18; Unc 18 homolog; Unc 18A; Unc-18A; Unc18 1; UNC18; Unc18 homolog; Unc18-1; Unc18A.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolSTXBP1
-
Short nameAnti-STXBP1 Ser515
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameSTXBP1(Ser515) Polyclonal Antibody
-
Alternative techniqueantibodies
-
Alternative to gene targetsyntaxin binding protein 1, MUNC18-1 and NSEC1 and P67 and RBSEC1 and UNC18, STXBP1 and IDBG-86143 and ENSG00000136854 and 6812, protein N-terminus binding, Plasma membranes, Stxbp1 and IDBG-161623 and ENSMUSG00000026797 and 20910, STXBP1 and IDBG-638972 and ENSBTAG00000003525 and 282378
-
Gene info
-
Identity
-
Gene
-
Long gene namesyntaxin binding protein 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1996-12-27
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data