STAT3 (Ser727) Antibody
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Catalog numberbs-3429R
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PricePlease ask
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Size0.1ml
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Long nameSTAT3 (Ser727) Primary Polyclonal Antibody
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Also known asSTAT3 (Ser727) PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenSTAT3 Ser727
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SpecificityThis is a highly specific antibody against STAT3 Ser727.
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Modification sPhosphorylation
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Modification site sSer727
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range710-740/770
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Subcellular locationCytoplasm, Nucleus
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SourceKLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Ser727
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Gene ID number6774
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Swiss ProtP40763
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenSignal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesAPRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSTAT3
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Short nameAnti-STAT3 Ser727
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameSTAT3 (Ser727) Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetsignal transducer and activator of transcription 3 (acute-phase response factor), ADMIO and APRF and HIES, STAT3 and IDBG-50702 and ENSG00000168610 and 6774, protein dimerization activity, nuclei, Stat3 and IDBG-211637 and ENSMUSG00000004040 and 20848, STAT3 and IDBG-640197 and ENSBTAG00000021523 and 101910056,508541
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Gene info
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Identity
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Gene
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Long gene namesignal transducer and activator of transcription 3
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Synonyms gene name
- signal transducer and activator of transcription 3 (acute-phase response factor)
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-11-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data