SSB Antibody

• Catalog number
  bs-0276R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SSB Primary Polyclonal Antibody
• Also known as
  SSB PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SSB
• Specificity
  This is a highly specific antibody against SSB.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SSB
• Gene ID number
  6741
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Lupus La protein (Sjogren syndrome type B antigen) (SS-B) (La ribonucleoprotein) (La autoantigen) plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S, 5S, 7S, and 7-2 RNAs. The phosphorylation sites are at the C-terminal part of the protein. Sera from patients with systemic lupus erythematosus(SLE) often contain that react with the normal cellular La protein as if this antigen was foreign.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  SSB; Lupus La protein homolog; La ribonucleoprotein; La autoantigen homolog; Sjogren syndrome type B antigen; LA_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SSB  
• Gene symbol
  SSB, SPSB1, SPSB4, SPSB3, SPSB2
• Short name
  Anti-SSB
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SSB Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11316
• Gene
  SSB
• Long gene name
  small RNA binding exonuclease protection factor La
• Synonyms gene name
  • Sjogren syndrome antigen B (autoantigen La)
  • Sjogren syndrome antigen B
• Synonyms
  • LARP3
  • La
  • La/SSB
• Synonyms name
  • La ribonucleoprotein domain family, member 3
  • Lupus La protein
  • La autoantigen
• Locus
  2q31.1
• Discovery year
  1990-09-10
• Entrez gene record
  6741
• Pubmed identfication
  • 2468131
  • 1692037
  • 28782243
• RefSeq identity
  • NM_003142
• Classification
  • La ribonucleoproteins
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000132212

Gene info

• Identity
  HGNC:30628
• Gene
  SPSB1
• Long gene name
  splA/ryanodine receptor domain and SOCS box containing 1
• Synonyms
  • SSB-1
• Locus
  1p36.22
• Discovery year
  2005-09-01
• Entrez gene record
  80176
• Pubmed identfication
  • 15713673
  • 12076535
• RefSeq identity
  • NM_025106
• VEGA ID
  OTTHUMG00000001279

Gene info

• Identity
  HGNC:30630
• Gene
  SPSB4
• Long gene name
  splA/ryanodine receptor domain and SOCS box containing 4
• Synonyms
  • SSB-4
• Locus
  3q23
• Discovery year
  2005-09-01
• Entrez gene record
  92369
• Pubmed identfication
  • 12076535
• RefSeq identity
  • NM_080862
• VEGA ID
  OTTHUMG00000160223

Gene info

• Identity
  HGNC:30629
• Gene
  SPSB3
• Long gene name
  splA/ryanodine receptor domain and SOCS box containing 3
• Synonyms gene
  • C16orf31
• Synonyms gene name
  • chromosome 16 open reading frame 31
• Synonyms
  • SSB-3
• Locus
  16p13.3
• Discovery year
  2005-09-01
• Entrez gene record
  90864
• Pubmed identfication
  • 12076535
• RefSeq identity
  • NM_080861
• VEGA ID
  OTTHUMG00000176746

Gene info

• Identity
  HGNC:29522
• Gene
  SPSB2
• Long gene name
  splA/ryanodine receptor domain and SOCS box containing 2
• Synonyms
  • GRCC9
  • SSB-2
• GenBank acession
  • AF403027
• Locus
  12p13.31
• Discovery year
  2005-09-01
• Entrez gene record
  84727
• Pubmed identfication
  • 8723724
  • 12076535
• RefSeq identity
  • NM_032641
• VEGA ID
  OTTHUMG00000156665

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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