SPP24 Antibody

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• Catalog number
  bs-8518R
• Price:

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• Size
  0.1ml

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• Long name
  SPP24 Primary Polyclonal Antibody
• Also known as
  SPP24 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SPP24
• Specificity
  This is a highly specific antibody against SPP24.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  65-100/211
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPP24/SPP2
• Gene ID number
  6694
• Swiss Prot
  Q13103
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  SPP24, also known as secreted phosphoprotein 2, is a 211 amino acid secreted protein that belongs to the cystatin superfamily. Expressed in liver and plasma, SPP24 may play a role in coordinating an aspect of bone turnover. The gene that encodes SPP24 maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes, making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  SPP24; SPP-24; Secreted phosphoprotein 24; Secreted phosphoprotein 2; SPP2
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

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• Gene target
  SPP24  
• Gene symbol
  SPP2
• Short name
  Anti-SPP24
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SPP24 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11256
• Gene
  SPP2
• Long gene name
  secreted phosphoprotein 2
• Synonyms gene name
  • secreted phosphoprotein 2, 24kD
  • secreted phosphoprotein 2, 24kDa
• Synonyms
  • SPP24
• Locus
  2q37.1
• Discovery year
  1996-08-21
• Entrez gene record
  6694
• Pubmed identfication
  • 9533032
• RefSeq identity
  • NM_006944
• VEGA ID
  OTTHUMG00000059208

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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