SPG21 Antibody
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Catalog numberbs-11785R
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PricePlease ask
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Size0.1ml
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Long nameSPG21 Primary Polyclonal Antibody
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Also known asSPG21 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenSPG21
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SpecificityThis is a highly specific antibody against SPG21.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPG21
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenMaspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesAcid cluster protein 33; ACP33; BM019; BM-019; GL010; MAST; Maspardin; Spastic paraplegia 21 autosomal recessive Mast syndrome protein; SPG21 antibody; SPG21_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSPG21
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Short nameAnti-SPG21
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameSPG21 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetspastic paraplegia 21 (autosomal recessive, Mast syndrome), SPG21 and IDBG-16930 and ENSG00000090487 and 51324, CD4 receptor binding, nuclei, Spg21 and IDBG-177905 and ENSMUSG00000032388 and 27965, SPG21 and IDBG-645311 and ENSBTAG00000011540 and 404069
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Gene info
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Identity
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Gene
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Long gene nameSPG21 abhydrolase domain containing, maspardin
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Synonyms gene name
- spastic paraplegia 21 (autosomal recessive, Mast syndrome)
- SPG21, maspardin
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-04-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Abhydrolase domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data