SPAG5 Antibody

• Catalog number
  bs-0717R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SPAG5 Primary Polyclonal Antibody
• Also known as
  SPAG5 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SPAG5
• Specificity
  This is a highly specific antibody against SPAG5.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1120-1170/1193
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPAG5/MAP126
• Gene ID number
  10615
• Swiss Prot
  Q96R06
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MAP126; DEEPEST; hMAP126; Sperm-associated antigen 5; Astrin; Mitotic spindle-associated protein p126; SPAG5
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SPAG5  
• Gene symbol
  SPAG5-AS1, SPAG5
• Short name
  Anti-SPAG5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SPAG5 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:41140
• Gene
  SPAG5-AS1
• Long gene name
  SPAG5 antisense RNA 1
• Synonyms gene name
  • SPAG5 antisense RNA 1 (non-protein coding)
• Locus
  17q11.2
• Discovery year
  2011-09-05
• Entrez gene record
  100506436
• Pubmed identfication
  • 31957155
• RefSeq identity
  • NR_040012
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000132827

Gene info

• Identity
  HGNC:13452
• Gene
  SPAG5
• Long gene name
  sperm associated antigen 5
• Synonyms
  • DEEPEST
  • MAP126
  • hMAP126
• Synonyms name
  • mitotic spindle coiled-coil related protein
  • astrin
  • mitotic spindle associated protein p126
• GenBank acession
  • AF063308
• Locus
  17q11.2
• Discovery year
  2002-10-08
• Entrez gene record
  10615
• Pubmed identfication
  • 11549262
• RefSeq identity
  • NM_006461
• VEGA ID
  OTTHUMG00000166586

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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