SorLA Antibody

• Catalog number
  bs-11166R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SorLA Primary Polyclonal Antibody
• Also known as
  SorLA PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SorLA
• Specificity
  This is a highly specific antibody against SorLA.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SorLA
• Gene ID number
  79845
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Sortilin-related receptor, also known as Sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL (the main cholesterol-carrying lipoprotein of plasma) and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP, receptor-associated protein. SorLa is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous sorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. It is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  C11orf32; FLJ21930; FLJ39258; gp250; LDLR relative with 11 ligand binding repeats; LDLR relative with 11 ligand-binding repeats; Low density lipoprotein receptor relative with 11 ligand binding repeats; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR 11; LR11; LRP 9; LRP9; Mosaic protein LR11; SORL 1; SORL_HUMAN; SORL1; SorLA 1; SorLA; SorLA-1; Sortilin related receptor; Sortilin related receptor LDLR class A repeats containing; Sortilin-related receptor; Sorting protein related receptor containing LDLR class A repeats; Sorting protein-related receptor containing LDLR class A repeats;
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SorLA  
• Gene symbol
  SORL1
• Short name
  Anti-SorLA
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SorLA Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11185
• Gene
  SORL1
• Long gene name
  sortilin related receptor 1
• Synonyms gene
  • C11orf32
• Synonyms gene name
  • chromosome 11 open reading frame 32
  • sortilin-related receptor, L(DLR class) A repeats-containing
• Synonyms
  • gp250
  • LR11
  • LRP9
  • SorLA
  • SorLA-1
• Synonyms name
  • LDLR relative with 11 ligand-binding repeats
• GenBank acession
  • Y08110
• Locus
  11q24.1
• Discovery year
  1996-12-27
• Entrez gene record
  6653
• Pubmed identfication
  • 9157966
  • 8940146
• RefSeq identity
  • NM_003105
• Classification
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000166057

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products