SLK Antibody

• Catalog number
  bs-3519R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SLK Primary Polyclonal Antibody
• Also known as
  SLK PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SLK
• Specificity
  This is a highly specific antibody against SLK.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLK
• Gene ID number
  9748
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1.The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR. Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of Fyn activity. Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Fyn; C syn protooncogene; FYN oncogene related to SRC FGR YESï¼› MGC45350; OKT3 induced calcium influx regulator; P59 FYN; Protein tyrosine kinase fyn; Proto oncogene tyrosine protein kinase fyn; Protooncogene Syn; SLK; Src like kinase; Src yes related novel gene; Src/yes related novel gene;SYN; Tyrosine kinase p59fyn T; Tyrosine kinase p59fynT.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SLK  
• Gene symbol
  FYN, SLK
• Short name
  Anti-SLK
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SLK Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  STE20-like kinase, bA16H23.1 and LOSK and se20-9 and STK2, SLK and IDBG-88663 and ENSG00000065613 and 9748, transferase activity, Cytoplasm, Slk and IDBG-174800 and ENSMUSG00000025060 and 20874, SLK and IDBG-639375 and ENSBTAG00000001017 and 535342

Gene info

• Identity
  HGNC:4037
• Gene
  FYN
• Long gene name
  FYN proto-oncogene, Src family tyrosine kinase
• Synonyms gene name
  • FYN oncogene related to SRC, FGR, YES
• Synonyms
  • SYN
  • SLK
  • MGC45350
• GenBank acession
  • AK056699
• Locus
  6q21
• Discovery year
  1988-08-19
• Entrez gene record
  2534
• Pubmed identfication
  • 3526330
• Classification
  • Src family tyrosine kinases
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000016305

Gene info

• Identity
  HGNC:11088
• Gene
  SLK
• Long gene name
  STE20 like kinase
• Synonyms gene name
  • SNF1 (sucrose nonfermenting, yeast, homolog)-like kinase, SNF1 sucrose nonfermenting like kinase (yeast)
  • STE20-like kinase (yeast)
  • STE20-like kinase
• Synonyms
  • STK2
  • se20-9
  • KIAA0204
• Locus
  10q24.33-q25.1
• Discovery year
  1992-04-16
• Entrez gene record
  9748
• Pubmed identfication
  • 3526554
• RefSeq identity
  • NM_014720
• VEGA ID
  OTTHUMG00000018999

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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