Six3 Antibody

• Catalog number
  bs-11970R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Six3 Primary Polyclonal Antibody
• Also known as
  Six3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Six3
• Specificity
  This is a highly specific antibody against Six3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Six3
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six3 is required for the specification and proliferation of the eye field in vertebrates and may be involved in some developmental disorders of the brain. Expression of Six3 is detected in human embryos as early as five to seven weeks of gestation, and is maintained in the eye throughout the entire period of fetal development. At 20 weeks of gestation, expression of Six3 in the human retina has been observed in ganglion cells and in cells of the inner nuclear layer. Six3 maps to human chromosome 2p16-p21, between genetic markers D2S119 and D2S288. The map position of human Six3 overlaps the positions of two dominant disorders (holoprosencephaly type 2 and Malattia leventinese) with ocular phenotypes that have been assigned to this chromosomal region.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Homeobox protein SIX3; HPE2; Sine oculis homeobox homolog 3; SIX homeobox 3; Six3; SIX3_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Six3  
• Gene symbol
  SIX3-AS1, SIX3
• Short name
  Anti-Six3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Six3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40532
• Gene
  SIX3-AS1
• Long gene name
  SIX3 antisense RNA 1
• Synonyms gene name
  • SIX3 antisense RNA 1 (non-protein coding)
• Synonyms
  • SIX3OS
• GenBank acession
  • BM690547
  • BM663835
• Locus
  2p21
• Discovery year
  2012-05-01
• Entrez gene record
  100506108
• Pubmed identfication
  • 15703187
• RefSeq identity
  • NR_103785
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000152423

Gene info

• Identity
  HGNC:10889
• Gene
  SIX3
• Long gene name
  SIX homeobox 3
• Synonyms gene
  • HPE2
• Synonyms gene name
  • holoprosencephaly 2, alobar or semilobar
  • sine oculis homeobox homolog 3 (Drosophila)
• GenBank acession
  • AF092047
• Locus
  2p21
• Discovery year
  1998-04-21
• Entrez gene record
  6496
• Pubmed identfication
  • 9889003
  • 10369266
• RefSeq identity
  • NM_005413
• Classification
  • SINE class homeoboxes
• VEGA ID
  OTTHUMG00000152424

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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